Human DNA levels in feces reflect gut inflammation and associate with presence of gut species in IBD patients across the age spectrum
The comprehensive characterization of human and microbiome fecal DNA is a useful approach to track immune response level and investigate the interaction that the immune system has with gut microbiome richness and composition over time, enriching opportunities for better disease monitoring and thus better treatment of IBD patients. Video Abstract.
Authors
- Shimrit Shmorak
- Ami Ben Yaʼacov (ORCID: https://orcid.org/0000-0001-7820-8299)
- Ruth Shemer (ORCID: https://orcid.org/0000-0003-0625-475X)
- Chiara Mazzoni (ORCID: https://orcid.org/0000-0002-0988-3108)
- Esty Harpenas
- Gili Focht
- Moran Yassour
- Raffi Lev-Tzion
- Bracha-Lea Ochana
- Oren Ledder
- Eyal Shteyer
- Esther Orlanski-Meyer
- Yuval Dor
Institutions
- Hebrew University of Jerusalem (IL)
- Jerusalem Institute for Israel Studies (IL)
- Shaare Zedek Medical Center (IL)
Publication Details
- Journal
- Microbiome
- Published
- 2026-02-25
- DOI
- https://doi.org/10.1186/s40168-026-02344-6
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00