Triple Primary Carcinomas of the Lung: A Case Report

Export Multiple primary lung cancers are relatively uncommon occurrences. Patients who have previously been treated for lung cancer are at risk of developing additional metachronous lung cancers. In this particular case, we present a 75-year-old female patient who experienced the development of three metachronous primary lung cancers, each with distinct histological variants. The initial tumor was identified as squamous cell carcinoma, which was successfully treated through concomitant chemoradiotherapy. Six years later, adenocarcinomas were detected and effectively managed using radiofrequency ablation. The third cancer was identified as metastatic small cell carcinoma, and it exhibited a favorable response to chemotherapy. This case serves as a significant reminder that patients who have undergone radical treatment for lung cancer require lifelong regular follow-up to monitor for potential recurrences or the development of new primary lung cancers.