A case of solitary bone plasmacytoma to multiple myeloma: a case report

Solitary bone plasmacytoma of the rib is uncommon but recognized. We report a case presenting with recurrent, predominantly nocturnal chest wall pain. Imaging revealed an expansile lesion on the left ninth rib and initially suggested fibrous/osteofibrous dysplasia. The patient underwent resection of the involved rib segment. Histopathology and immunohistochemistry confirmed solitary bone plasmacytoma. The patient declined the recommended adjuvant radiotherapy. Twenty-one months later, the disease progressed to multiple myeloma.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-02-25
DOI
https://doi.org/10.3389/fmed.2026.1774242
Primary Topic
Multiple Myeloma Research and Treatments
Type
article
Field-Weighted Citation Impact
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article

A case of solitary bone plasmacytoma to multiple myeloma: a case report

Zhimin Fang, Yuguang Ma Jiacong Shen, Cheng Zhu, Zhongcong He et al.
Frontiers in Medicine
Multiple Myeloma Research and Treatments
article

A case of solitary bone plasmacytoma to multiple myeloma: a case report

Zhimin Fang, Yuguang Ma Jiacong Shen, Cheng Zhu, Zhongcong He, Huangyu Luo, Zhong Tian, Bo Lei, Ni Fu, Jiyang Tang
article en

Abstract

Solitary bone plasmacytoma of the rib is uncommon but recognized. We report a case presenting with recurrent, predominantly nocturnal chest wall pain. Imaging revealed an expansile lesion on the left ninth rib and initially suggested fibrous/osteofibrous dysplasia. The patient underwent resection of the involved rib segment. Histopathology and immunohistochemistry confirmed solitary bone plasmacytoma. The patient declined the recommended adjuvant radiotherapy. Twenty-one months later, the disease progressed to multiple myeloma.

Frontiers in MedicineVol. 13
Zunyi Medical University (CN), Affiliated Hospital of Zunyi Medical College (CN)
Good health and well-being
Openalex Percentile: Top 43%
Multiple Myeloma Research and Treatments
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