AC005034.3/hsa-miR-126-5p/EIF3H axis: bioinformatics analysis, expression validation, and association with prognosis and immunosuppressive microenvironment in pancreatic adenocarcinoma

Our findings indicate that ncRNA-driven overexpression of EIF3H is associated with poor prognosis and tumor immune cell infiltration in PAAD, suggesting that the AC005034.3/hsa-miR-126-5p/EIF3H axis may serve as a promising prognostic biomarker and therapeutic target in PAAD.

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Publication Details

Journal
Frontiers in Cell and Developmental Biology
Published
2026-02-25
DOI
https://doi.org/10.3389/fcell.2026.1725060
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

AC005034.3/hsa-miR-126-5p/EIF3H axis: bioinformatics analysis, expression validation, and association with prognosis and immunosuppressive microenvironment in pancreatic adenocarcinoma

Song Wen, Zhixin Song, Kai Sun, X Wang et al.
Frontiers in Cell and Developmental Biology
Ferroptosis and cancer prognosis
article

AC005034.3/hsa-miR-126-5p/EIF3H axis: bioinformatics analysis, expression validation, and association with prognosis and immunosuppressive microenvironment in pancreatic adenocarcinoma

Song Wen, Zhixin Song, Kai Sun, X Wang, Yi-lian Qiu, Ke-run Wang, Xiao-yun Zhang
article en

Abstract

Our findings indicate that ncRNA-driven overexpression of EIF3H is associated with poor prognosis and tumor immune cell infiltration in PAAD, suggesting that the AC005034.3/hsa-miR-126-5p/EIF3H axis may serve as a promising prognostic biomarker and therapeutic target in PAAD.

Frontiers in Cell and Developmental BiologyVol. 14
Hexi University (CN), First Affiliated Hospital of Gannan Medical University (CN)
Partnerships for the goals
Openalex Percentile: Top 44%
Ferroptosis and cancer prognosis
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