Influence of antiviral treatment in hepatitis C patients on metabolism and fibrosis process

DAA therapy significantly alters metabolic and inflammatory biomarkers in HCV patients, with regimen- and fibrosis stage-specific effects. S/V may provide broader metabolic benefits in advanced disease, while G/P offers stronger anti-inflammatory responses earlier, supporting personalized treatment approaches.

Authors

Filip M. Szymański (ORCID: https://orcid.org/0000-0002-2638-7894)
Krzysztof Tomasiewicz (ORCID: https://orcid.org/0000-0001-7868-2708)
Malwina Jędrysik (ORCID: https://orcid.org/0000-0002-0156-2588)
Beata Chełstowska (ORCID: https://orcid.org/0000-0002-0671-101X)
Magdalena Tudrujek-Zdunek

Institutions

Medical University of Lublin (PL)
Cardinal Stefan Wyszynski University in Warsaw (PL)

Publication Details

Journal: Frontiers in Medicine
Published: 2026-02-25
DOI: https://doi.org/10.3389/fmed.2026.1729835
Primary Topic: Liver Disease Diagnosis and Treatment
Type: article
Field-Weighted Citation Impact: 0.00

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article

Influence of antiviral treatment in hepatitis C patients on metabolism and fibrosis process

Filip M. Szymański, Krzysztof Tomasiewicz, Malwina Jędrysik, Beata Chełstowska et al.

Feb 25, 2026

Frontiers in Medicine

Liver Disease Diagnosis and Treatment

article

Influence of antiviral treatment in hepatitis C patients on metabolism and fibrosis process

Filip M. Szymański, Krzysztof Tomasiewicz, Malwina Jędrysik, Beata Chełstowska, Magdalena Tudrujek-Zdunek

February 25, 2026article en

Abstract

DAA therapy significantly alters metabolic and inflammatory biomarkers in HCV patients, with regimen- and fibrosis stage-specific effects. S/V may provide broader metabolic benefits in advanced disease, while G/P offers stronger anti-inflammatory responses earlier, supporting personalized treatment approaches.

Frontiers in MedicineVol. 13

Medical University of Lublin (PL), Cardinal Stefan Wyszynski University in Warsaw (PL)

Good health and well-being

Openalex Percentile: Top 44%

Liver Disease Diagnosis and Treatment

DOI Open Access PDF OpenAlex

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