Fine-needle muscle microbiopsy: a feasible and well-tolerated alternative for skeletal muscle sampling
Fine-needle muscle microbiopsy using a 20-gauge needle is well tolerated, with pain comparable to routine venipuncture. This approach substantially reduces invasiveness compared to traditional biopsies while providing adequate material for proteomic analysis. These findings support its ethical and practical application in sensitive populations and longitudinal research.
Authors
- Johan Jakobsson (ORCID: https://orcid.org/0000-0002-9816-194X)
- Apostolos Theos (ORCID: https://orcid.org/0000-0001-8191-6659)
- Michael Svensson (ORCID: https://orcid.org/0000-0003-4972-4416)
- Christer Malm (ORCID: https://orcid.org/0000-0002-8436-2476)
- Karin Strigård
Institutions
- Umeå University (SE)
Publication Details
- Journal
- Frontiers in Physiology
- Published
- 2026-02-25
- DOI
- https://doi.org/10.3389/fphys.2026.1783535
- Primary Topic
- Exercise and Physiological Responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Umeå Universitet