Ozonated Water Modulates Cell Proliferation and Vascular Density in Solid Ehrlich Tumor of Mice
Ozonated water reduced tumor cell proliferation in the medium term, but treatment discontinuation favored increased vascular density in the long term. These findings suggest caution in the oncological use of ozone, as it may present both antineoplastic and tumor-promoting effects depending on treatment conditions.
Authors
- Mariana Batista Rodrigues Faleiro (ORCID: https://orcid.org/0000-0003-2589-1308)
- Daniela Petrim de Araújo
- Cleusely Matias de Souza (ORCID: https://orcid.org/0000-0003-2024-0784)
- Emmanuel Arnhold (ORCID: https://orcid.org/0000-0003-0922-146X)
- Juliana Santana de Curcio (ORCID: https://orcid.org/0000-0003-2978-3689)
- Veridiana Maria Brianezi Dignani de Moura
- Elisângela de Paula Silveira Lacerda
- Eduardo de Paula Nascente
- Carlos Eduardo Fonseca-Alves
Institutions
- Universidade Federal de Goiás (BR)
- Universidade Estadual Paulista (Unesp) (BR)
Publication Details
- Journal
- Cancers
- Published
- 2026-02-25
- DOI
- https://doi.org/10.3390/cancers18050733
- Primary Topic
- Medical and Biological Ozone Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Directorate for Biological Sciences