Vertically infected Aedes aegypti excrete infectious arboviruses in saliva

These findings suggest that vertical transmission may be an underestimated mechanism which provides a potential route by which Ae. aegypti can become infective independently of biting a viremic host, thereby contributing to arbovirus persistence and spread. The presence of infected male progeny also demonstrates that vertically transmitted viruses can persist in mosquito populations even in individuals that do not blood-feed.

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Publication Details

Journal
BMC Biology
Published
2026-02-25
DOI
https://doi.org/10.1186/s12915-026-02562-2
Primary Topic
Mosquito-borne diseases and control
Type
article
Field-Weighted Citation Impact
0.00
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article

Vertically infected Aedes aegypti excrete infectious arboviruses in saliva

Anubis Vega-Rúa, Christelle Dollin, Elodie Calvez, Gladys Gutiérrez et al.
BMC Biology
Mosquito-borne diseases and control
article

Vertically infected Aedes aegypti excrete infectious arboviruses in saliva

Anubis Vega-Rúa, Christelle Dollin, Elodie Calvez, Gladys Gutiérrez, Yanet Martínez, Xavier de Lamballerie, Géraldine Piorkowski
article en

Abstract

These findings suggest that vertical transmission may be an underestimated mechanism which provides a potential route by which Ae. aegypti can become infective independently of biting a viremic host, thereby contributing to arbovirus persistence and spread. The presence of infected male progeny also demonstrates that vertically transmitted viruses can persist in mosquito populations even in individuals that do not blood-feed.

BMC Biology
Johns Hopkins University (US), Inserm (FR), Aix-Marseille Université (FR), Institut Pasteur de la Guadeloupe (GP), Instituto de Medicina Tropical “Pedro Kourí” (CU), Institut de Recherche pour le Développement (FR)
Good health and well-being
Openalex Percentile: Top 47%
Mosquito-borne diseases and control
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