Group-based trajectory modeling of platelet dynamics in sepsis: from phenotypic identification to the exploration of prognostic mediators

Dynamic modeling of platelet count trajectories enables effective identification of clinically meaningful subphenotypes in sepsis patients, offering a robust framework for prognosis prediction. This approach supports refined risk stratification and personalized management strategies, thereby providing novel insights into the pathophysiology and clinical care of sepsis.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-02-25
DOI
https://doi.org/10.3389/fmed.2026.1761545
Primary Topic
Sepsis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Group-based trajectory modeling of platelet dynamics in sepsis: from phenotypic identification to the exploration of prognostic mediators

Jundan Cai, Fang Ye, Hua Yang, Wu Yun et al.
Frontiers in Medicine
Sepsis Diagnosis and Treatment
article

Group-based trajectory modeling of platelet dynamics in sepsis: from phenotypic identification to the exploration of prognostic mediators

Jundan Cai, Fang Ye, Hua Yang, Wu Yun, Chunhui Ni, Xi Zhang, Yingying Ma
article en

Abstract

Dynamic modeling of platelet count trajectories enables effective identification of clinically meaningful subphenotypes in sepsis patients, offering a robust framework for prognosis prediction. This approach supports refined risk stratification and personalized management strategies, thereby providing novel insights into the pathophysiology and clinical care of sepsis.

Frontiers in MedicineVol. 13
Jiangsu University (CN), Nantong University (CN), Affiliated Hospital of Nantong University (CN), Affiliated Hospital of Jiangsu University (CN)
Jiangsu University
Good health and well-being
Openalex Percentile: Top 44%
Sepsis Diagnosis and Treatment
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