Group-based trajectory modeling of platelet dynamics in sepsis: from phenotypic identification to the exploration of prognostic mediators
Dynamic modeling of platelet count trajectories enables effective identification of clinically meaningful subphenotypes in sepsis patients, offering a robust framework for prognosis prediction. This approach supports refined risk stratification and personalized management strategies, thereby providing novel insights into the pathophysiology and clinical care of sepsis.
Authors
- Jundan Cai
- Fang Ye
- Hua Yang (ORCID: https://orcid.org/0000-0002-5518-5255)
- Wu Yun (ORCID: https://orcid.org/0009-0002-1108-760X)
- Chunhui Ni
- Xi Zhang
- Yingying Ma
Institutions
- Jiangsu University (CN)
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
- Affiliated Hospital of Jiangsu University (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-02-25
- DOI
- https://doi.org/10.3389/fmed.2026.1761545
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Jiangsu University