Nivolumab induces seven-year sustained remission in a patient with advanced PD-L1-positive lung adenocarcinoma: a case report

For patients with PD-L1-high advanced NSCLC, nivolumab monotherapy can induce deep and durable immune responses, enabling long-term survival with a manageable safety profile, even in elderly patients with multiple comorbidities. This case provides compelling real-world evidence for the remarkable efficacy of immune checkpoint inhibitors.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-02-25
DOI
https://doi.org/10.3389/fonc.2026.1742382
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
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article

Nivolumab induces seven-year sustained remission in a patient with advanced PD-L1-positive lung adenocarcinoma: a case report

Xing Wang, Qihong Yu, Hongmei Sheng, Wei Zhang et al.
Frontiers in Oncology
Cancer Immunotherapy and Biomarkers
article

Nivolumab induces seven-year sustained remission in a patient with advanced PD-L1-positive lung adenocarcinoma: a case report

Xing Wang, Qihong Yu, Hongmei Sheng, Wei Zhang, Haiying Peng
article en

Abstract

For patients with PD-L1-high advanced NSCLC, nivolumab monotherapy can induce deep and durable immune responses, enabling long-term survival with a manageable safety profile, even in elderly patients with multiple comorbidities. This case provides compelling real-world evidence for the remarkable efficacy of immune checkpoint inhibitors.

Frontiers in OncologyVol. 16
Tianjin Chest Hospital (CN)
Openalex Percentile: Top 42%
Cancer Immunotherapy and Biomarkers
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