Physiological effect and pharmacokinetic evaluation of combined oral administration of cannabidiolic acid and cannabigerolic acid in dogs

An equal blend of primarily CBDA and CBGA whole hemp acidic cannabinoid rich oil in soft gel appears to be well tolerated by dogs over a 90 day period with no adverse events. Pharmacokinetics are like other CBDA and CBGA studies in dogs with surprising concentrations of the other minor cannabinoids THCA and CBCA. Considering the favorable absorption/retention profile of the acidic cannabinoids, further research for therapeutic interventions for inflammatory conditions and organ dysfunction should be considered.