Synergistic interactions of melatonin and glucocorticoids in alleviating allergic airway inflammation

Melatonin, when combined with corticosteroids, may represent a promising therapeutic strategy for allergic asthma, potentially improving asthma control through modulation of inflammation and circadian rhythm regulation. Further studies are needed to fully elucidate the mechanisms underlying this synergy and to evaluate the long-term therapeutic benefits.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-02-25
DOI
https://doi.org/10.3389/fmed.2026.1738965
Primary Topic
Circadian rhythm and melatonin
Type
article
Field-Weighted Citation Impact
0.00
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article

Synergistic interactions of melatonin and glucocorticoids in alleviating allergic airway inflammation

Xinyi Zhang, Guilian Chen, Yi-Xiang Wang, Ting Ma et al.
Frontiers in Medicine
Circadian rhythm and melatonin
article

Synergistic interactions of melatonin and glucocorticoids in alleviating allergic airway inflammation

Xinyi Zhang, Guilian Chen, Yi-Xiang Wang, Ting Ma, Zhe Zhang, Baolan Wang
article en

Abstract

Melatonin, when combined with corticosteroids, may represent a promising therapeutic strategy for allergic asthma, potentially improving asthma control through modulation of inflammation and circadian rhythm regulation. Further studies are needed to fully elucidate the mechanisms underlying this synergy and to evaluate the long-term therapeutic benefits.

Frontiers in MedicineVol. 13
Xuzhou Medical College (CN), Soochow University (CN), Second People’s Hospital of Huai’an (CN), First Affiliated Hospital of Soochow University (CN), Nanjing Medical University (CN)
Good health and well-being
Openalex Percentile: Top 39%
Circadian rhythm and melatonin
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