Circadian IOP Rhythm in Rats Is Driven by Neural Signals From the Brain
The IOP rhythm in rats is driven by sympathetic efferent signals from a central circadian clock. Ocular clocks and circulating humoral factors do not appear to contribute to rhythmogenesis. The neural pathway of circadian pressure control may be relevant to glaucoma pathophysiology.
Authors
- Christopher L. Passaglia (ORCID: https://orcid.org/0000-0001-5902-9818)
- Alexandra Zamitalo-Pomares
Institutions
- University of South Florida (US)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2026-02-25
- DOI
- https://doi.org/10.1167/iovs.67.2.53
- Primary Topic
- Circadian rhythm and melatonin
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health