Single-cell hdWGCNA and experimental validation identify an innovative T-cell-associated prognostic model and immune microenvironment in lung adenocarcinoma with lymph node metastasis

The T-cell marker gene-based prognostic risk model provides a foundation for evaluating the prognosis of lymph node-metastatic LUAD and shows potential for optimizing targeted therapy and immunotherapy strategies.

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Publication Details

Journal
BMC Cancer
Published
2026-02-25
DOI
https://doi.org/10.1186/s12885-026-15649-4
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Single-cell hdWGCNA and experimental validation identify an innovative T-cell-associated prognostic model and immune microenvironment in lung adenocarcinoma with lymph node metastasis

Lijun Zeng, Sixuan Wu, Yuehua Li
BMC Cancer
Ferroptosis and cancer prognosis
article

Single-cell hdWGCNA and experimental validation identify an innovative T-cell-associated prognostic model and immune microenvironment in lung adenocarcinoma with lymph node metastasis

Lijun Zeng, Sixuan Wu, Yuehua Li
article en

Abstract

The T-cell marker gene-based prognostic risk model provides a foundation for evaluating the prognosis of lymph node-metastatic LUAD and shows potential for optimizing targeted therapy and immunotherapy strategies.

BMC Cancer
First Affiliated Hospital of University of South China (CN), University of South China (CN)
Good health and well-being
Openalex Percentile: Top 44%
Ferroptosis and cancer prognosis
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