Tumor-specific antibody cocktail treatment suppresses colorectal tumor growth in mice

Our findings establish a proof-of-concept for individualized, mutation-guided antibody therapies, supporting further development of this approach to improve outcomes in patients with advanced CRC.

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Publication Details

Journal
Cancer Immunology Immunotherapy
Published
2026-02-25
DOI
https://doi.org/10.1007/s00262-026-04337-8
Primary Topic
Monoclonal and Polyclonal Antibodies Research
Type
article
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article

Tumor-specific antibody cocktail treatment suppresses colorectal tumor growth in mice

Stephanie C. Pero, Yujing Sun, David N. Krag, Linda Mei et al.
Cancer Immunology Immunotherapy
Monoclonal and Polyclonal Antibodies Research
article

Tumor-specific antibody cocktail treatment suppresses colorectal tumor growth in mice

Stephanie C. Pero, Yujing Sun, David N. Krag, Linda Mei, Girja S. Shukla, Margaret E. Ackerman, Matthew R. Fournier
article en

Abstract

Our findings establish a proof-of-concept for individualized, mutation-guided antibody therapies, supporting further development of this approach to improve outcomes in patients with advanced CRC.

Cancer Immunology ImmunotherapyVol. 75(3)
Dartmouth College (US), University of Vermont (US), Shelburne Museum (US)
Good health and well-being
Openalex Percentile: Top 45%
Monoclonal and Polyclonal Antibodies Research
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