Reference intervals for blood concentrations of folate-related biomarkers in early pregnancy among pregnant women in Qingdao

This study characterized the distribution of RBC folate, vitamin B12, homocysteine, and 5-MTHF concentrations in early pregnancy (9-13<sup>+ 6</sup> weeks) and established RIs across different age, BMI, and total folate intake subgroups in Qingdao population. These findings provide valuable reference data for clinicians and laboratory researchers.

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Publication Details

Journal
BMC Pregnancy and Childbirth
Published
2026-02-25
DOI
https://doi.org/10.1186/s12884-026-08869-w
Primary Topic
Folate and B Vitamins Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Reference intervals for blood concentrations of folate-related biomarkers in early pregnancy among pregnant women in Qingdao

Xueteng Ding, Caiping Xiang, Jinbao Zhu, Haiyan Liu et al.
BMC Pregnancy and Childbirth
Folate and B Vitamins Research
article

Reference intervals for blood concentrations of folate-related biomarkers in early pregnancy among pregnant women in Qingdao

Xueteng Ding, Caiping Xiang, Jinbao Zhu, Haiyan Liu, Min Cao, Yaguang Peng, Yanfang Li, Guoju Li
article en

Abstract

This study characterized the distribution of RBC folate, vitamin B12, homocysteine, and 5-MTHF concentrations in early pregnancy (9-13<sup>+ 6</sup> weeks) and established RIs across different age, BMI, and total folate intake subgroups in Qingdao population. These findings provide valuable reference data for clinicians and laboratory researchers.

BMC Pregnancy and Childbirth
Qingdao University (CN), Heze Medical College (CN), Beijing Children’s Hospital (CN), Qingdao Municipal Center for Disease Control and Prevention (CN), Qingdao Women and Children's Hospital (CN)
Openalex Percentile: Top 46%
Folate and B Vitamins Research
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