Chronological age, proton pump inhibitors in older adults, and diabetes in older adults on physicochemical characteristics of contents of the descending duodenum during fasting: An exploratory study
Based on data collected in this study, the effect of chronological age, PPIs in older adults and/or Type II diabetes in older adults on the pH, buffer capacity or bile acids concentrations in the fasted duodenal contents appears to be too small to impact oral drug absorption.
Authors
- Adam Asteriadis
- Christos Reppas (ORCID: https://orcid.org/0000-0002-6958-2147)
- Konstantinos Goumas
- Maria Vertzoni
- Theodoros Argyropoulos
- Ekaterina Bocharova
Institutions
- National and Kapodistrian University of Athens (GR)
- Hellenic Red Cross (GR)
- General Hospital of Athens G. Genimatas (GR)
- IASO General Hospital (GR)
Publication Details
- Journal
- European Journal of Pharmaceutical Sciences
- Published
- 2026-02-25
- DOI
- https://doi.org/10.1016/j.ejps.2026.107489
- Primary Topic
- Dietary Effects on Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00