Individual chemotherapy for patients colorectal cancer based on patient-derived tumor-like cell clusters

Accounting for patient's pathological and clinical characteristics, PTC-based drug-sensitivity testing can help accurately identify effective agents for CRC <i>in vitro</i>. This novel preclinical platform may reduce unnecessary chemotherapy and support precision oncology.

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Publication Details

Journal
World Journal of Gastrointestinal Surgery
Published
2026-02-25
DOI
https://doi.org/10.4240/wjgs.v18.i2.114286
Primary Topic
Cancer Cells and Metastasis
Type
article
Field-Weighted Citation Impact
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article

Individual chemotherapy for patients colorectal cancer based on patient-derived tumor-like cell clusters

Xiaolong Luo, Fulin Lin, Ji-Guang Xie, Yun-Jie Ye et al.
World Journal of Gastrointestinal Surgery
Cancer Cells and Metastasis
article

Individual chemotherapy for patients colorectal cancer based on patient-derived tumor-like cell clusters

Xiaolong Luo, Fulin Lin, Ji-Guang Xie, Yun-Jie Ye, Bing-Feng Jin, Zhen-Dong Liu, Xue-Lin Ji, Li-Min Zhou, Si-Qi Chen
article en

Abstract

Accounting for patient's pathological and clinical characteristics, PTC-based drug-sensitivity testing can help accurately identify effective agents for CRC <i>in vitro</i>. This novel preclinical platform may reduce unnecessary chemotherapy and support precision oncology.

World Journal of Gastrointestinal SurgeryVol. 18(2)
Zhejiang Chinese Medical University (CN), 117th Hospital of People's Liberation Army (CN), Zhejiang Hospital (CN)
Openalex Percentile: Top 42%
Cancer Cells and Metastasis
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