Routine inflammatory indices modify clonal hematopoiesis-related prognostic risk in patients undergoing percutaneous coronary intervention: a real-world cohort study

Hematopoiesis-related genetic alterations conferred excess prognostic risk, primarily in the presence of elevated hematological inflammation, underscoring the potential benefit of inflammatory burden management in PCI patients harboring CHIP.

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Publication Details

Journal
BMC Medicine
Published
2026-02-25
DOI
https://doi.org/10.1186/s12916-026-04711-4
Primary Topic
Inflammatory Biomarkers in Disease Prognosis
Type
article
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article

Routine inflammatory indices modify clonal hematopoiesis-related prognostic risk in patients undergoing percutaneous coronary intervention: a real-world cohort study

Xuefeng Lu, Kailun Yan, Bo Xu, Xuxiang Shen et al.
BMC Medicine
Inflammatory Biomarkers in Disease Prognosis
article

Routine inflammatory indices modify clonal hematopoiesis-related prognostic risk in patients undergoing percutaneous coronary intervention: a real-world cohort study

Xuefeng Lu, Kailun Yan, Bo Xu, Xuxiang Shen, Ru Liu, Mengyang Du, Keyong Huang, Guyu Zeng, Ying Song, Jiawen Li, Ping Jiang, Hangyi Zhao, Jingjing Xu, Huanhuan Wang, Dongfeng Gu, Shufeng Chen, Jianxin Li, Menglu Liu, Hongfan Li, Runlin Gao, Yuejin Yang, Xueyan Zhao, Tianyu Li, Jie Cao, Fangchao Liu, Kexin Zhang
article en

Abstract

Hematopoiesis-related genetic alterations conferred excess prognostic risk, primarily in the presence of elevated hematological inflammation, underscoring the potential benefit of inflammatory burden management in PCI patients harboring CHIP.

BMC Medicine
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Southern University of Science and Technology (CN), State Key Laboratory of Respiratory Disease (CN), Fu Wai Hospital (CN), Guangzhou Medical University (CN)
Good health and well-being
Openalex Percentile: Top 42%
Inflammatory Biomarkers in Disease Prognosis
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