Composite patient-reported outcomes and risk prediction for overall survival in advanced non-small cell lung cancer with first-line cemiplimab

In patients with advanced NSCLC receiving first-line cemiplimab-based therapy, composite PROs consisting of one functioning and one symptom scale had greater prognostic value than single PRO scales. Further development and analysis of composite PROs for clinical trials is warranted.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-02-25
DOI
https://doi.org/10.3389/fonc.2026.1676687
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
0.00

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article

Composite patient-reported outcomes and risk prediction for overall survival in advanced non-small cell lung cancer with first-line cemiplimab

Mahmut Gumus, J. Harnett, Eric Yan, Miranda Gogishvili et al.
Frontiers in Oncology
Lung Cancer Treatments and Mutations
article

Composite patient-reported outcomes and risk prediction for overall survival in advanced non-small cell lung cancer with first-line cemiplimab

Mahmut Gumus, J. Harnett, Eric Yan, Miranda Gogishvili, Ahmet Sezer, David Gandara, Tamta Makharadze, Ruben G. W. Quek
article en

Abstract

In patients with advanced NSCLC receiving first-line cemiplimab-based therapy, composite PROs consisting of one functioning and one symptom scale had greater prognostic value than single PRO scales. Further development and analysis of composite PROs for clinical trials is warranted.

Frontiers in OncologyVol. 16
Regeneron (United States) (US), Başkent University (TR), Highland Hospital (US), Global College (CY), Sylvester Comprehensive Cancer Center (US), Medical Technologies (Czechia) (CZ), Istanbul Medeniyet University (TR)
Sanofi, Regeneron Pharmaceuticals
Openalex Percentile: Top 44%
Lung Cancer Treatments and Mutations
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