A 12-gene immune signature predicts prognosis and identifies KRT6B as a therapeutic target in lung adenocarcinoma

We established and validated an immune-related gene signature for prognostic prediction and identified KRT6B as a promising prognostic biomarker and potential therapeutic target in LUAD.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-02-25
DOI
https://doi.org/10.3389/fimmu.2026.1693469
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

A 12-gene immune signature predicts prognosis and identifies KRT6B as a therapeutic target in lung adenocarcinoma

Rongqi Jiang, Jinhuo Lai, Yahua Wu, Mingliang Shi et al.
Frontiers in Immunology
Ferroptosis and cancer prognosis
article

A 12-gene immune signature predicts prognosis and identifies KRT6B as a therapeutic target in lung adenocarcinoma

Rongqi Jiang, Jinhuo Lai, Yahua Wu, Mingliang Shi, Weiwei Gu, Jiude Qi
article en

Abstract

We established and validated an immune-related gene signature for prognostic prediction and identified KRT6B as a promising prognostic biomarker and potential therapeutic target in LUAD.

Frontiers in ImmunologyVol. 17
Fujian Medical University (CN), Shandong Provincial Hospital (CN), Shandong First Medical University (CN)
Good health and well-being
Openalex Percentile: Top 44%
Ferroptosis and cancer prognosis
DOIOpen Access PDFOpenAlex
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