Prognostic significance and regulatory role of ACOT7 in the tumor immune microenvironment of breast invasive ductal carcinoma: a multi-omics analysis
Our study indicates that elevated ACOT7 expression is a significant marker of adverse clinical outcomes. This effect it likely mediated through the remodeling of the tumor immune microenvironment and the reprogramming of metabolic pathways, which collectively fuel the malignant procession of IDC. These results provide a solid theoretical foundation for targeting ACOT7 as both a prognostic biomarker and a potential therapeutic target in IDC.
Authors
- ChongHui SONG
- Y. Chen
- Juan Du (ORCID: https://orcid.org/0000-0002-9498-5423)
- Yuxin Shan
- Y. Quan
- Kunwei Li
- Ning Li
Institutions
- Kunming University of Science and Technology (CN)
- Yunnan Maternal and Child Health (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-25
- DOI
- https://doi.org/10.3389/fimmu.2026.1735908
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Kunming University of Science and Technology