Identification of KRAS mutation in rectal cancer based on a 2.5D deep learning model

A 2.5D deep learning model can effectively distinguish between KRAS mutant and KRAS wild-type RC, outperforming traditional radiomic models. It provides a novel non-invasive approach for the preoperative assessment of KRAS mutation status.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-02-25
DOI
https://doi.org/10.3389/fonc.2026.1763859
Primary Topic
Radiomics and Machine Learning in Medical Imaging
Type
article
Field-Weighted Citation Impact
0.00
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article

Identification of KRAS mutation in rectal cancer based on a 2.5D deep learning model

Guanfeng Chen, Chengmeng Zhang, Yanyan Zhou, H. P. Peng et al.
Frontiers in Oncology
Radiomics and Machine Learning in Medical Imaging
article

Identification of KRAS mutation in rectal cancer based on a 2.5D deep learning model

Guanfeng Chen, Chengmeng Zhang, Yanyan Zhou, H. P. Peng, Jinge Li, Jian Shen
article en

Abstract

A 2.5D deep learning model can effectively distinguish between KRAS mutant and KRAS wild-type RC, outperforming traditional radiomic models. It provides a novel non-invasive approach for the preoperative assessment of KRAS mutation status.

Frontiers in OncologyVol. 16
Zhejiang Chinese Medical University (CN), Fujian Medical University (CN), Huzhou Normal University (CN), Huzhou Central Hospital (CN), First Affiliated Hospital of Fujian Medical University (CN), County Hospital (GB)
Openalex Percentile: Top 45%
Radiomics and Machine Learning in Medical Imaging
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