Grey matter volume reduction in the cerebellum of hip osteoarthritis patients: insights from pre- and postoperative VBM analysis

The findings provide preliminary evidence of cerebellar GM changes in patients requiring hip prostheses, suggesting central nervous system involvement in chronic hip pathology. Interpretation is constrained by the modest sample size and by variability in postoperative imaging intervals. The absence of significant postoperative changes highlights the need for further research to explore the timeline and extent of neuroplastic recovery. These results underscore the importance of considering central adaptations in the management of peripheral joint disorders.

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Publication Details

Journal
La radiologia medica
Published
2026-02-25
DOI
https://doi.org/10.1007/s11547-026-02184-2
Primary Topic
Orthopaedic implants and arthroplasty
Type
article
Field-Weighted Citation Impact
0.00
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article

Grey matter volume reduction in the cerebellum of hip osteoarthritis patients: insights from pre- and postoperative VBM analysis

Maddalena Boccia, Marco Fiorelli, Gumina Stefano, Alice Teghil et al.
La radiologia medica
Orthopaedic implants and arthroplasty
article

Grey matter volume reduction in the cerebellum of hip osteoarthritis patients: insights from pre- and postoperative VBM analysis

Maddalena Boccia, Marco Fiorelli, Gumina Stefano, Alice Teghil, Francesca Caramia, Alessandro Calistri, Valentina Calistri, Costanza Giannì
article en

Abstract

The findings provide preliminary evidence of cerebellar GM changes in patients requiring hip prostheses, suggesting central nervous system involvement in chronic hip pathology. Interpretation is constrained by the modest sample size and by variability in postoperative imaging intervals. The absence of significant postoperative changes highlights the need for further research to explore the timeline and extent of neuroplastic recovery. These results underscore the importance of considering central adaptations in the management of peripheral joint disorders.

La radiologia medica
Fondazione Santa Lucia (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT), Sapienza University of Rome (IT)
Openalex Percentile: Top 44%
Orthopaedic implants and arthroplasty
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