Grey matter volume reduction in the cerebellum of hip osteoarthritis patients: insights from pre- and postoperative VBM analysis
The findings provide preliminary evidence of cerebellar GM changes in patients requiring hip prostheses, suggesting central nervous system involvement in chronic hip pathology. Interpretation is constrained by the modest sample size and by variability in postoperative imaging intervals. The absence of significant postoperative changes highlights the need for further research to explore the timeline and extent of neuroplastic recovery. These results underscore the importance of considering central adaptations in the management of peripheral joint disorders.
Authors
- Maddalena Boccia (ORCID: https://orcid.org/0000-0002-2044-8326)
- Marco Fiorelli (ORCID: https://orcid.org/0000-0003-0235-0146)
- Gumina Stefano
- Alice Teghil (ORCID: https://orcid.org/0000-0003-3689-3376)
- Francesca Caramia (ORCID: https://orcid.org/0000-0002-8396-1282)
- Alessandro Calistri (ORCID: https://orcid.org/0000-0001-5832-8437)
- Valentina Calistri
- Costanza Giannì
Institutions
- Fondazione Santa Lucia (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- La radiologia medica
- Published
- 2026-02-25
- DOI
- https://doi.org/10.1007/s11547-026-02184-2
- Primary Topic
- Orthopaedic implants and arthroplasty
- Type
- article
- Field-Weighted Citation Impact
- 0.00