High-intensity intermittent training promotes adipose tissue browning via the IL-27/p38 MAPK–PGC-1α signaling pathway in diet-induced obese rats
HIIT promotes adipose tissue browning by activating the IL-27 signalling pathway and ameliorates obesity-associated metabolic disorders more effectively than MAIT, supporting its potential as a therapeutic strategy for obesity.
Authors
- Yinyin Wu (ORCID: https://orcid.org/0009-0000-7107-4830)
- Chunlong Wang
- Yulong Hu
- Junfei Chen
Institutions
- Shanghai Research Institute of Sports Science (CN)
- Yangzhou Vocational University (CN)
- Yangzhou University (CN)
Publication Details
- Journal
- Frontiers in Physiology
- Published
- 2026-02-25
- DOI
- https://doi.org/10.3389/fphys.2026.1745363
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- China Postdoctoral Science Foundation
- Yangzhou University