Thioredoxin 1 Suppresses TXNIP-Driven Control of Glucose Metabolism in Human Cells
This study reveals that the key intracellular redox protein TRX inversely regulates TXNIP, suggesting that modulation of the TRX system may provide a previously unrecognized therapeutic avenue for modulation of glucose metabolism. <i>Antioxid. Redox Signal.</i> 00, 000-000.
Authors
- Lucia Coppo (ORCID: https://orcid.org/0000-0001-6902-6346)
- Elias S.J. Arnér (ORCID: https://orcid.org/0000-0002-4807-6114)
- Peter Geserick
- Markus Dagnell (ORCID: https://orcid.org/0000-0002-5925-6794)
- Shayida Maimaiti
- Kai Kappert
Institutions
- Karolinska Institutet (SE)
- National Institute of Oncology (HU)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Antioxidants and Redox Signaling
- Published
- 2026-02-24
- DOI
- https://doi.org/10.1177/15230864261421616
- Primary Topic
- Redox biology and oxidative stress
- Type
- article
- Field-Weighted Citation Impact
- 0.00