A novel epigenetic regulation of JAM-A by EZH2-DNMT3A cascade contributes to T cell adhesion via the activation of Rap1a in lupus patients
This research reveals a novel epigenetic regulation of JAM-A by EZH2-DNMT3A cascade contributes to T cell adhesion capacity via the activation of Rap1a/β1-integrin in lupus patients.
Authors
- Y. S. Lin (ORCID: https://orcid.org/0000-0001-5905-8336)
- Huan Gu (ORCID: https://orcid.org/0000-0001-7300-6997)
- Ni An (ORCID: https://orcid.org/0000-0001-7332-8654)
- Lei Ding (ORCID: https://orcid.org/0000-0003-4680-1180)
- Yu Han (ORCID: https://orcid.org/0000-0001-5507-9228)
- Xi Zhang (ORCID: https://orcid.org/0000-0002-4638-3997)
- Liwei Yang
- Yuting Zhong (ORCID: https://orcid.org/0009-0008-7381-1628)
- Min Yu
- Wen Lin
- Haoling Song
- Hongjian Chen
- Xuexiu Chang
- Qingchun Lei
Institutions
- Kunming University (CN)
- Yunnan University (CN)
- First People's Hospital of Yunnan Province (CN)
- Deyang Stomatological Hospital (CN)
- Luoyang Central Hospital Affiliated to Zhengzhou University (CN)
- Yunnan Institute of Environmental Sciences (CN)
- Puer University (CN)
Publication Details
- Journal
- Journal of Translational Autoimmunity
- Published
- 2026-02-25
- DOI
- https://doi.org/10.1016/j.jtauto.2026.100362
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.00