Nocturnal Melatonin Deficiency in Colorectal Cancer: Independent Predictive Value Beyond Sleep Quality

Although cancer patients and the control group showed comparable obstructive sleep apnea risk, sleep quality was poorer, and melatonin levels were significantly lower in the cancer group. Melatonin assessment can complement traditional risk stratification and may provide new insights into the interplay between circadian biology, sleep, and colorectal carcinogenesis.

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Publication Details

Journal
The Turkish Journal of Gastroenterology
Published
2026-02-23
DOI
https://doi.org/10.5152/tjg.2026.25808
Primary Topic
Circadian rhythm and melatonin
Type
article
Field-Weighted Citation Impact
0.00

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article

Nocturnal Melatonin Deficiency in Colorectal Cancer: Independent Predictive Value Beyond Sleep Quality

Musa E. Yilmaz, Muhammed Kaya, Duygu Özol, Büşra Durak et al.
The Turkish Journal of Gastroenterology
Circadian rhythm and melatonin
article

Nocturnal Melatonin Deficiency in Colorectal Cancer: Independent Predictive Value Beyond Sleep Quality

Musa E. Yilmaz, Muhammed Kaya, Duygu Özol, Büşra Durak, İbrahim Durak, Huseyin Koseoglu
article en

Abstract

Although cancer patients and the control group showed comparable obstructive sleep apnea risk, sleep quality was poorer, and melatonin levels were significantly lower in the cancer group. Melatonin assessment can complement traditional risk stratification and may provide new insights into the interplay between circadian biology, sleep, and colorectal carcinogenesis.

The Turkish Journal of Gastroenterology
University of Health Science (KH), Hitit Üniversitesi (TR), Samsun University (TR), Sağlık Bilimleri Üniversitesi (TR), University of Health Sciences Antigua (AG)
Hitit Üniversitesi
Reduced inequalities
Openalex Percentile: Top 40%
Circadian rhythm and melatonin
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