Effects of Xipayi Gingival Solution combined with minocycline hydrochloride on inflammatory cytokines and masticatory function in patients with chronic periodontitis

Xipayi Gingival Solution combined with minocycline hydrochloride enhances periodontal status, mitigates inflammatory and oxidative stress responses, improves masticatory function, and relieves pain without increasing adverse events. The combined therapy demonstrates better clinical efficacy than minocycline alone, indicating a safe and effective therapeutic approach for chronic periodontitis.

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Publication Details

Journal
Frontiers in Cellular and Infection Microbiology
Published
2026-02-25
DOI
https://doi.org/10.3389/fcimb.2026.1739777
Primary Topic
Oral microbiology and periodontitis research
Type
article
Field-Weighted Citation Impact
0.00
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article

Effects of Xipayi Gingival Solution combined with minocycline hydrochloride on inflammatory cytokines and masticatory function in patients with chronic periodontitis

Yanjie Chai, Lijie Xu, Shenxi Yao, Meijie Shen
Frontiers in Cellular and Infection Microbiology
Oral microbiology and periodontitis research
article

Effects of Xipayi Gingival Solution combined with minocycline hydrochloride on inflammatory cytokines and masticatory function in patients with chronic periodontitis

Yanjie Chai, Lijie Xu, Shenxi Yao, Meijie Shen
article en

Abstract

Xipayi Gingival Solution combined with minocycline hydrochloride enhances periodontal status, mitigates inflammatory and oxidative stress responses, improves masticatory function, and relieves pain without increasing adverse events. The combined therapy demonstrates better clinical efficacy than minocycline alone, indicating a safe and effective therapeutic approach for chronic periodontitis.

Frontiers in Cellular and Infection MicrobiologyVol. 16
Tongde Hospital of Zhejiang Province (CN)
Good health and well-being
Openalex Percentile: Top 45%
Oral microbiology and periodontitis research
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