Effects of Xipayi Gingival Solution combined with minocycline hydrochloride on inflammatory cytokines and masticatory function in patients with chronic periodontitis
Xipayi Gingival Solution combined with minocycline hydrochloride enhances periodontal status, mitigates inflammatory and oxidative stress responses, improves masticatory function, and relieves pain without increasing adverse events. The combined therapy demonstrates better clinical efficacy than minocycline alone, indicating a safe and effective therapeutic approach for chronic periodontitis.
Authors
- Yanjie Chai
- Lijie Xu
- Shenxi Yao
- Meijie Shen
Institutions
- Tongde Hospital of Zhejiang Province (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2026-02-25
- DOI
- https://doi.org/10.3389/fcimb.2026.1739777
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00