Pattern of disease recurrence and outcomes after progression of high-risk renal cell carcinoma (RCC) patients treated with adjuvant immunotherapy

High-risk RCC patients treated with adjuvant immunotherapy remain at considerable risk of relapse, frequently with oligometastatic disease. Excellent post-progression outcomes after loco-regional treatment support a multidisciplinary, metastasis-directed approach to recurrence after adjuvant immunotherapy.

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Publication Details

Journal
Cancer Immunology Immunotherapy
Published
2026-02-25
DOI
https://doi.org/10.1007/s00262-026-04331-0
Primary Topic
Renal cell carcinoma treatment
Type
article
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article

Pattern of disease recurrence and outcomes after progression of high-risk renal cell carcinoma (RCC) patients treated with adjuvant immunotherapy

Romina Rose Pedone, Alessio Neri, Chiara Ligato, Gloria Messina et al.
Cancer Immunology Immunotherapy
Renal cell carcinoma treatment
article

Pattern of disease recurrence and outcomes after progression of high-risk renal cell carcinoma (RCC) patients treated with adjuvant immunotherapy

Romina Rose Pedone, Alessio Neri, Chiara Ligato, Gloria Messina, Valeria Sardaro, Denis Occhipinti, Daniela Arduini, Luca Tagliaferri, Rachele Belletto, Rexhina Ajdhoni, Paola Troisi, Luigi Roca, Maria Antonia Fucile, Chiara CICCARESE, Giampaolo Tortora, Bernardo Rocco, Davide Di Leo, Roberto Iacovelli, Fabiana Caliciotti
article en

Abstract

High-risk RCC patients treated with adjuvant immunotherapy remain at considerable risk of relapse, frequently with oligometastatic disease. Excellent post-progression outcomes after loco-regional treatment support a multidisciplinary, metastasis-directed approach to recurrence after adjuvant immunotherapy.

Cancer Immunology ImmunotherapyVol. 75(3)
Università Cattolica del Sacro Cuore (IT), Agostino Gemelli University Polyclinic (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Good health and well-being
Openalex Percentile: Top 44%
Renal cell carcinoma treatment
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