Eccentric treadmill training and skeletal muscle immunometabolic responses in HFD-induced insulin resistance
Moderate-intensity eccentric treadmill training ameliorates HFD-induced skeletal muscle IR, likely driven by AKT-mediated reduction in pro-inflammatory M1 macrophage polarization.
Authors
- Lei Ai (ORCID: https://orcid.org/0000-0002-8406-3900)
- Shijin Zhao (ORCID: https://orcid.org/0009-0001-9168-1221)
- Yuanyuan Wang (ORCID: https://orcid.org/0000-0003-1420-0567)
- Wei Luo (ORCID: https://orcid.org/0000-0001-5051-6476)
- Siyi He
- Yue Zhou
Institutions
- Nanjing Sport Institute (CN)
- Shanghai Research Institute of Sports Science (CN)
- Beijing Sport University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-25
- DOI
- https://doi.org/10.3389/fimmu.2026.1757925
- Primary Topic
- Exercise and Physiological Responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Government of Jiangsu Province