Diffusion MRI sampling schemes bias diffusion metrics and tractography
These findings demonstrate systematic differences in voxel-wise metrics and tractography outcomes from four diffusion-sampling schemes. In addition to qualitatively informing attempts to consolidate or contrast data across schemes, future work could explore regression-based harmonization-and other methods-to reduce residual bias and enable pooled analyses across diverse protocols.
Authors
- Diego Szczupak (ORCID: https://orcid.org/0000-0003-0818-9613)
- Marina Monteiro
- Ivanei E. Bramati (ORCID: https://orcid.org/0000-0001-8721-9053)
- Fernanda Tovar‐Moll
- Ryan J. Dean (ORCID: https://orcid.org/0000-0002-7146-1352)
- Fernanda Meireles
- Daniel Menezes Guimarães
Institutions
- California Institute of Technology (US)
- University of Pittsburgh (US)
- Washington University in St. Louis (US)
- Washington University Medical Center (US)
- Laboratoire Plasticité du Cerveau (FR)
- Centre d'études et de recherches internationales de Sciences Po (FR)
- Institute of Neurobiology (BG)
Publication Details
- Journal
- Frontiers in Neuroimaging
- Published
- 2026-02-25
- DOI
- https://doi.org/10.3389/fnimg.2026.1670604
- Primary Topic
- Advanced Neuroimaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00