Pallidal and subthalamic deep brain stimulation for cranio-cervical dystonia: Optimal stimulation sites and a convergent pathway
Our work provides a network-based explanation for the comparable efficacy of GPi and STN stimulation, suggesting that therapeutic benefit is driven by modulating specific pathways rather than the nucleus alone. This provides a new framework for refining and personalizing therapy.
Authors
- Zixiao. Yin
- Tianxue Hu
- Anchao Yang (ORCID: https://orcid.org/0000-0001-9179-5571)
- Tianqi Hu
- Hutao Xie (ORCID: https://orcid.org/0000-0003-3725-5085)
- Zehua Zhao (ORCID: https://orcid.org/0009-0000-3337-0102)
- Tao Xue
- Jurgen Germann
- Tiantian Hua
- Ningfei Li
- Houyou Fan
- Gavin Elias
- Yin Jiang
- Alexandre Boutet
- Yichen Xu
- Andres M. Lozano
- Huanguang Liu
- Jianguo Zhang
- Yutong Bai
- Andreas Horn
- Zijian Guo
Institutions
- Capital Medical University (CN)
- Beijing Tian Tan Hospital (CN)
- Massachusetts General Hospital (US)
- Beijing Institute of Neurosurgery (CN)
- Ontario Brain Institute (CA)
- Krembil Brain Institute
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Neurobiology of Disease
- Published
- 2026-02-25
- DOI
- https://doi.org/10.1016/j.nbd.2026.107331
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00