Platelet-derived mediators in hospitalized COVID-19 patients and associations to respiratory failure, ICU admittance and 60-day mortality
Our findings underscore the role of platelet-derived inflammatory mediators in the pathogenesis of COVID-19, potentially involving direct effects of SARS-CoV-2. The study also points to a persistent platelet activation following hospitalization.
Authors
- Anne Hege Aamodt (ORCID: https://orcid.org/0000-0002-2824-2760)
- Thor Ueland (ORCID: https://orcid.org/0000-0001-5005-0784)
- Ylva Schanke
- Anders Aune Tveita (ORCID: https://orcid.org/0000-0002-0668-9262)
- Tuva Børresdatter Dahl (ORCID: https://orcid.org/0000-0001-7818-9411)
- Beathe Kiland Granerud (ORCID: https://orcid.org/0000-0002-6951-2317)
- Jan Cato Holter
- Kristian Tonby
- P Aukrust
- A E Michelsen
- Lars Heggelund
- Anne Ma Dyrhol-Riise
- Mari Kaarbø
- Aleksander Rygh Holten
- Bente Halvorsen
Institutions
- Oslo University Hospital (NO)
- University Hospital of North Norway (NO)
- University of Liverpool (GB)
- University of Oslo (NO)
- Norwegian University of Science and Technology (NO)
- Drammen Hospital (NO)
- Vestre Viken Hospital Trust (NO)
- Thrombosis Research Institute (GB)
- University of Bergen (NO)
- UiT The Arctic University of Norway (NO)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2026-02-25
- DOI
- https://doi.org/10.3389/fcvm.2026.1685861
- Primary Topic
- COVID-19 Clinical Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission
- Norges Forskningsråd
- Helse Sør-Øst RHF