Artificial intelligence in osteoporosis assessment using CT imaging: a scoping review

Current evidence shows that AI-enhanced CT can achieve diagnostic and screening performance comparable to DXA and QCT, although fracture-risk prediction still requires improvement through multimodal data integration. However, methodological heterogeneity and the lack of standardized workflows limit cross-study comparability and clinical translation. Integrating AI into routine CT pipelines may reduce screening costs, enable earlier detection and intervention, and help mitigate the global burden of osteoporosis.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-02-24
DOI
https://doi.org/10.3389/fmed.2026.1779483
Primary Topic
Artificial Intelligence in Healthcare and Education
Type
article
Field-Weighted Citation Impact
0.00
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article

Artificial intelligence in osteoporosis assessment using CT imaging: a scoping review

Y Y zhang, Yuhui Kou, Yi Yang, Meng Meng et al.
Frontiers in Medicine
Artificial Intelligence in Healthcare and Education
article

Artificial intelligence in osteoporosis assessment using CT imaging: a scoping review

Y Y zhang, Yuhui Kou, Yi Yang, Meng Meng, Yuyang Ran, Hanwen Cheng, Simin Liu
article en

Abstract

Current evidence shows that AI-enhanced CT can achieve diagnostic and screening performance comparable to DXA and QCT, although fracture-risk prediction still requires improvement through multimodal data integration. However, methodological heterogeneity and the lack of standardized workflows limit cross-study comparability and clinical translation. Integrating AI into routine CT pipelines may reduce screening costs, enable earlier detection and intervention, and help mitigate the global burden of osteoporosis.

Frontiers in MedicineVol. 13
China Aerospace Science and Industry Corporation (China) (CN), Changzhi Medical College (CN), Peking University (CN), Second Affiliated Hospital of Guangzhou Medical University (CN), Peking University People's Hospital (CN), Guangzhou Medical University (CN), Tsinghua University (CN)
Openalex Percentile: Top 46%
Artificial Intelligence in Healthcare and Education
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