Racial and ethnic differences in the impact of air pollution on the risk of Alzheimer’s disease and related dementias in the Multiethnic Cohort Study

In this multiethnic population, incidence of ADRD increased with exposures to PM<sub>2.5</sub>, aUFP, and NO<sub>2</sub> in all subjects and this pattern was most prominent among African American adults. These results emphasize that ADRD prevention should include not only individual-level factors but also population-wide policies and regulation to curb air pollution.

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Publication Details

Journal
Environment International
Published
2026-02-25
DOI
https://doi.org/10.1016/j.envint.2026.110169
Primary Topic
Air Quality and Health Impacts
Type
article
Field-Weighted Citation Impact
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article

Racial and ethnic differences in the impact of air pollution on the risk of Alzheimer’s disease and related dementias in the Multiethnic Cohort Study

D. O. Stram, Scott Fruin, Beate R. Ritz, V. Wendy Setiawan et al.
Environment International
Air Quality and Health Impacts
article

Racial and ethnic differences in the impact of air pollution on the risk of Alzheimer’s disease and related dementias in the Multiethnic Cohort Study

D. O. Stram, Scott Fruin, Beate R. Ritz, V. Wendy Setiawan, Iona Cheng, Chiuchen Tseng, Lynne R. Wilkens, Eileen M. Crimmins, Howard Hu, Burcu F. Darst, Christopher Haiman, Timothy Larson, Jun Wu, Song-Yi Park, Anna H. Wu, Loïc Le Marchand
article en

Abstract

In this multiethnic population, incidence of ADRD increased with exposures to PM<sub>2.5</sub>, aUFP, and NO<sub>2</sub> in all subjects and this pattern was most prominent among African American adults. These results emphasize that ADRD prevention should include not only individual-level factors but also population-wide policies and regulation to curb air pollution.

Environment InternationalVol. 209
University of Southern California (US), University of Hawaiʻi at Mānoa (US), Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa (ZA), Hawaii Pacific University (US), University of California, Los Angeles (US), University of California, San Francisco (US), University of Washington (US), Fred Hutch Cancer Center (US), Cancer Center of Hawaii (US), Faculty of Public Health (GB)
Openalex Percentile: Top 49%
Air Quality and Health Impacts
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