Risk Stratified Breast Cancer Screening: Early Outcomes and Psychological Impact from PRSONAL – a Randomized Clinical Trial
Risk-stratified breast cancer screening is feasible and de-escalated screening acceptable for low-risk women. Automated risk communication has minimal - if any - impact on short-term psychological well-being. Final conclusions await prespecified 800 days end-of-follow-up.
Authors
- S. Bojesen
- Ilse Vejborg (ORCID: https://orcid.org/0000-0002-2329-203X)
- Lorenzo Ficorella (ORCID: https://orcid.org/0000-0002-0577-1571)
- John S. Dennis (ORCID: https://orcid.org/0000-0002-0323-2136)
- Line Hjøllund Pedersen (ORCID: https://orcid.org/0000-0001-7305-098X)
- Janne Bigaard (ORCID: https://orcid.org/0000-0001-8561-3145)
- Berit Andersen
- Pia R. Kamstrup
- Henrik Flyger
- Xin Yang
- Antonis C. Antoniou
Institutions
- University of Cambridge (GB)
- Herlev Hospital (DK)
- Aarhus University Hospital (DK)
- Copenhagen University Hospital (DK)
- Gentofte Hospital (DK)
- Danish Cancer Society (DK)
Publication Details
- Journal
- The Breast
- Published
- 2026-02-24
- DOI
- https://doi.org/10.1016/j.breast.2026.104743
- Primary Topic
- Global Cancer Incidence and Screening
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Cancer Research UK
- National Institute for Health and Care Research
- Department of Health and Social Care
- Gentofte Hospital
- Novo Nordisk
- Novo Nordisk Fonden
- NIHR Cambridge Biomedical Research Centre