UNITe: exploiting conserved links between oncogenesis and homeostasis to identify novel cancer drivers
Overall, we presented a first comparative analysis of cancer drivers with conserved homeostatic processes, suggesting a complementary approach to prioritizing cancer drivers. The model and the codes are freely available for public usage at https://github.com/hannenhalli-lab/conserved_links_homeostasis_oncogenesis.
Authors
- Sridhar Hannenhalli (ORCID: https://orcid.org/0000-0001-9603-7569)
- Annan Timon
- Arashdeep Singh (ORCID: https://orcid.org/0000-0001-6087-7240)
- Vishaka Gopalan
- Piyush Agrawal
Institutions
- National Institutes of Health (US)
- California University of Pennsylvania (US)
- Trichy SRM Medical College Hospital and Research Centre (IN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-02-24
- DOI
- https://doi.org/10.3389/fonc.2026.1711517
- Primary Topic
- Bioinformatics and Genomic Networks
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Cancer Institute