Acquired generalised lipodystrophy as an uncommon complication of anti-Mi-2 dermatomyositis: a case report

Fig. 2. Clinical manifestations of acquired generalised lipodystrophy in an anti-Mi-2-positive dermatomyositis patient.A: Proximal upper-arm adipose atrophy with prominence of muscular and bony contours.B: Facial lipoatrophy with loss of volume in the cheeks, perioral region, and jawline, accentuating nasolabial folds.C: Symmetrical reduction of subcutaneous adipose tissue in the femoral region.D: Bilateral gluteal lipoatrophy with decreased contour and loss of adipose prominence.The distribution pattern is symmetrical and cephalocaudal, typical of acquired lipodystrophy in inflammatory myopathies.