Hormonal contraceptives and EEG biomarkers for antidepressant treatment response in women

Although hormonal contraceptive use is not associated with EEG-biomarkers in unmedicated depressed women, they may modulate links between specific EEG-biomarkers and antidepressant response. However, contraceptive use, specifically COC, is associated with worse treatment outcomes and may be critical to developing biomarkers, including EEG-based, to guide treatment in women with MDD.

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Publication Details

Journal
Communications Medicine
Published
2026-02-24
DOI
https://doi.org/10.1038/s43856-026-01438-4
Primary Topic
Menopause: Health Impacts and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Hormonal contraceptives and EEG biomarkers for antidepressant treatment response in women

K. H. R. Jensen, V. G. Frokjaer, M. B. Jørgensen, A. K. Juvik et al.
Communications Medicine
Menopause: Health Impacts and Treatments
article

Hormonal contraceptives and EEG biomarkers for antidepressant treatment response in women

K. H. R. Jensen, V. G. Frokjaer, M. B. Jørgensen, A. K. Juvik, C. T. Ip, M. T. Andersen, S. V. Larsen
article en

Abstract

Although hormonal contraceptive use is not associated with EEG-biomarkers in unmedicated depressed women, they may modulate links between specific EEG-biomarkers and antidepressant response. However, contraceptive use, specifically COC, is associated with worse treatment outcomes and may be critical to developing biomarkers, including EEG-based, to guide treatment in women with MDD.

Communications Medicine
University of Copenhagen (DK), University of Macau (MO), Rigshospitalet (DK)
Innovationsfonden, Lundbeckfonden, Universidade de Macau, Region Hovedstaden, H. Lundbeck A/S
Good health and well-being
Openalex Percentile: Top 46%
Menopause: Health Impacts and Treatments
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