Review of the Performance of Laboratory-Based Molecular Diagnostics for <i>Chlamydia trachomatis</i> and <i>Neisseria gonorrhoeae</i>
Future directions include expanding FDA clearance for self-collected extragenital specimens and developing viability assays to better distinguish active infection from residual nucleic acids. Together, these advances underscore the progress in CT/NG testing and highlight opportunities to further improve diagnostic reach and clinical relevance.
Authors
- Julio C. Ayala (ORCID: https://orcid.org/0000-0001-9998-3091)
- Megan Crumpler
- Shelby M. Hutton
- Salika M. Shakir (ORCID: https://orcid.org/0000-0003-4642-8574)
- William W. Davis (ORCID: https://orcid.org/0000-0001-7062-9531)
- Amanda Smith
- Susan E. Realegeno
- Barbara Van Der Pol
Institutions
- University of Alabama at Birmingham (US)
- ARUP Laboratories (United States) (US)
- National Center for HIV/AIDS Viral Hepatitis STD and TB Prevention (US)
- Orange County Healthcare Agency (US)
- Quest Diagnostics (United States) (US)
Publication Details
- Journal
- Clinical Infectious Diseases
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1093/cid/ciaf696
- Primary Topic
- Reproductive tract infections research
- Type
- article
- Field-Weighted Citation Impact
- 0.00