Diagnosis of acute appendicitis at a pediatric emergency department within a general hospital

Ultrasound (US) has evolved as the principal imaging modality in the evaluation of pediatric appendicitis due to inherent advantages but may vary in performance based on setting. Rapid focused Magnetic Resonance Imaging (rapid MRI) is a feasible alternative, but emergency department (ED) length of stay (LOS) may be impacted. We wished to determine the performance and LOS of US and rapid MRI in a pediatric ED within a general hospital in the evaluation of appendicitis. We conducted a retrospective diagnostic accuracy study of patients < 18 years of age with abdominal pain receiving imaging for evaluation of appendicitis (US or rapid MRI). We report descriptive statistics on demographics and clinical characteristics of the study population. We conducted a sensitivity analysis by the different imaging type and combinations performed. Sensitivity and specificity for US and rapid MRI were 65.3% (95% CI: 57.5%–72.5%); 97.0% (95% CI: 94.5%–98.5%) and 98.3% (95% CI: 90.6%–100.0%); 96.1%, (95% CI: 91.1%–98.7%), respectively. US alone was associated with the shortest median ED LOS (5.3 hours, IQR 3.9–7.8), followed by rapid MRI alone (7.9 hours, IQR 5.4–8.6). US with subsequent rapid MRI was associated with the longest ED LOS (10.6 hours, IQR 7.6–13.3). US was nondiagnostic for a substantial number of studies performed resulting in suboptimal sensitivity for the diagnosis of appendicitis. Rapid MRI had better sensitivity but a greater LOS. Future work should focus on determining potential barriers that exist and incorporating strategies to enhance US performance and/or decrease rapid MRI LOS.

Authors

Institutions

Publication Details

Journal
Emergency Radiology
Published
2026-02-24
DOI
https://doi.org/10.1007/s10140-026-02442-w
Primary Topic
Appendicitis Diagnosis and Management
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Diagnosis of acute appendicitis at a pediatric emergency department within a general hospital

Hei Kit Chan, Catherine M. Pivalizza, KUOJEN TSAO, Robert M. Lapus et al.
Emergency Radiology
Appendicitis Diagnosis and Management
article

Diagnosis of acute appendicitis at a pediatric emergency department within a general hospital

Hei Kit Chan, Catherine M. Pivalizza, KUOJEN TSAO, Robert M. Lapus, Megan Kaes Long, Susan D. John, Hannah Smith, Cade A. Johnson
article en

Abstract

Ultrasound (US) has evolved as the principal imaging modality in the evaluation of pediatric appendicitis due to inherent advantages but may vary in performance based on setting. Rapid focused Magnetic Resonance Imaging (rapid MRI) is a feasible alternative, but emergency department (ED) length of stay (LOS) may be impacted. We wished to determine the performance and LOS of US and rapid MRI in a pediatric ED within a general hospital in the evaluation of appendicitis. We conducted a retrospective diagnostic accuracy study of patients < 18 years of age with abdominal pain receiving imaging for evaluation of appendicitis (US or rapid MRI). We report descriptive statistics on demographics and clinical characteristics of the study population. We conducted a sensitivity analysis by the different imaging type and combinations performed. Sensitivity and specificity for US and rapid MRI were 65.3% (95% CI: 57.5%–72.5%); 97.0% (95% CI: 94.5%–98.5%) and 98.3% (95% CI: 90.6%–100.0%); 96.1%, (95% CI: 91.1%–98.7%), respectively. US alone was associated with the shortest median ED LOS (5.3 hours, IQR 3.9–7.8), followed by rapid MRI alone (7.9 hours, IQR 5.4–8.6). US with subsequent rapid MRI was associated with the longest ED LOS (10.6 hours, IQR 7.6–13.3). US was nondiagnostic for a substantial number of studies performed resulting in suboptimal sensitivity for the diagnosis of appendicitis. Rapid MRI had better sensitivity but a greater LOS. Future work should focus on determining potential barriers that exist and incorporating strategies to enhance US performance and/or decrease rapid MRI LOS.

Emergency Radiology
Memorial Hermann (US), University of Chicago (US), Harvard Affiliated Emergency Medicine Residency (US), The University of Texas Health Science Center (US), The University of Texas Health Science Center at Houston (US)
Openalex Percentile: Top 47%
Appendicitis Diagnosis and Management
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.