Two-Stage Surgery in Patients with Diffuse Glioma—Indications, Implications and Outcome
Planned two-stage surgery was mostly performed as a surgical strategy in eloquent locations to achieve supramaximal or maximal resection. A two-staged surgery significantly extended resection results without neurological and functional deterioration. Despite relevant complication rates, primary debulking followed by staged resection as well as two-staged multifocal approaches may yield a favourable risk-benefit profile.
Authors
- Sebastian Jeising (ORCID: https://orcid.org/0000-0002-2130-7082)
- Franziska Staub‐Bartelt (ORCID: https://orcid.org/0000-0003-0191-566X)
- Johannes Reinken
- Michael Sabel
- Marion Rapp
Institutions
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- Universitätsklinikum Gießen und Marburg (DE)
- Universitätsklinikum Erlangen (DE)
- Giessen School of Theology (DE)
- Life & Brain (Germany) (DE)
- Heinrich Heine University Düsseldorf (DE)
Publication Details
- Journal
- Cancers
- Published
- 2026-02-24
- DOI
- https://doi.org/10.3390/cancers18050722
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00