Unveiling the hidden genetic conundrum linking pulmonary diseases and neuropsychiatric disorders: Novel insights from advanced omics-based analyses of the lung-brain axis
These findings indicate that pleiotropic genetic factors connecting pulmonary and neuropsychiatric diseases are widely distributed throughout the genome. This provides robust evidence for a shared genetic basis underlying the LBA and has important implications for the potential for developing targeted intervention and treatment that simultaneously address both diseases types.
Authors
- Shuting Ding
- Na Sun (ORCID: https://orcid.org/0000-0003-1433-8283)
- Hongzhi Ji
- Minghao Wu
- Xiaohua Zhao
- Weiqiang Su
- Zhen Zhang
- Min Fu
- Peicheng Wang
- Bingqiang Zhang
- Yujia Kong
- Manli Zhao
- Mengyao Gao
- Bing Han
- Chenyu Ma
Institutions
- Qingdao University (CN)
- Weifang Medical University (CN)
- Qingdao University of Science and Technology (CN)
- Weifang People's Hospital (CN)
- Affiliated Hospital of Qingdao University (CN)
- Weifang Chinese Medicine Hospital (CN)
Publication Details
- Journal
- Neurobiology of Disease
- Published
- 2026-02-25
- DOI
- https://doi.org/10.1016/j.nbd.2026.107333
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00