Case Report: Bevacizumab combined with chemotherapy followed by PARP inhibitor maintenance therapy in POLE-mutated primary fallopian tube carcinoma: a case of precision treatment in a rare gynecologic malignancy
This case demonstrates that Bev combined with chemotherapy may be an effective first-line regimen for this rare PTC variant. Maintenance therapy with a PARP inhibitor may prolong progression-free survival.
Authors
- Donghai Cheng
- Xiujie Liu
- Wenyuan He
- Peng Liu
- Xueqin Huang
Institutions
- University of Nottingham Ningbo China (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-02-24
- DOI
- https://doi.org/10.3389/fmed.2026.1696996
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00