Evaluation of pre-operative endometrial biopsy accuracy and etiological distribution in abnormal uterine bleeding using the PALM–COEIN classification

Among patients undergoing hysterectomy for AUB, structural pathologies, particularly leiomyomas, constitute the primary reason for hysterectomy. Although pre-operative EB is successful in ruling out pathologies, it may be insufficient in detecting focal lesions and some pre-malignant conditions due to its low sensitivity. Therefore, EB results should be supported by advanced diagnostic imaging methods, especially when clinical suspicion exists during the decision-making process for hysterectomy.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-02-24
DOI
https://doi.org/10.3389/fmed.2026.1784420
Primary Topic
Gynecological conditions and treatments
Type
article
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article

Evaluation of pre-operative endometrial biopsy accuracy and etiological distribution in abnormal uterine bleeding using the PALM–COEIN classification

Muhammet Bora Uzuner, Oğuzhan Karakoç, Yasemin Ercan Değirmenci, E. Emre et al.
Frontiers in Medicine
Gynecological conditions and treatments
article

Evaluation of pre-operative endometrial biopsy accuracy and etiological distribution in abnormal uterine bleeding using the PALM–COEIN classification

Muhammet Bora Uzuner, Oğuzhan Karakoç, Yasemin Ercan Değirmenci, E. Emre, Nazli Sener, Mustafa Ata Aydin, Alihan TIĞLI, Rulin Deniz, Yakup Baykus, Guzide Ece Akinci, Suleyman Aydin, Erdem Gurkan
article en

Abstract

Among patients undergoing hysterectomy for AUB, structural pathologies, particularly leiomyomas, constitute the primary reason for hysterectomy. Although pre-operative EB is successful in ruling out pathologies, it may be insufficient in detecting focal lesions and some pre-malignant conditions due to its low sensitivity. Therefore, EB results should be supported by advanced diagnostic imaging methods, especially when clinical suspicion exists during the decision-making process for hysterectomy.

Frontiers in MedicineVol. 13
Fırat University (TR), Banadir Hospital (SO), Bandırma Onyedi Eylül University (TR), Gazi Hastanesi (TR), Gazi University (TR)
Good health and well-being
Openalex Percentile: Top 41%
Gynecological conditions and treatments
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