Valproate Use by Fathers and Risk of Neurodevelopmental Disorders in Children

Paternal use of valproate within the 90 days before conception was not associated with an increased risk of NDDs in offspring after adjustment for confounding in Norwegian and Taiwanese cohorts. (Funded by the Research Council of Norway and the National Science and Technology Council of Taiwan.).

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Publication Details

Journal
NEJM Evidence
Published
2026-02-24
DOI
https://doi.org/10.1056/evidoa2500254
Citations
1
Primary Topic
Pharmacological Effects and Toxicity Studies
Type
article
Field-Weighted Citation Impact
41.22
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article

Valproate Use by Fathers and Risk of Neurodevelopmental Disorders in Children

Hui-Min Chuang, Marleen M. H. J. van Gelder, Li Chen, HC Lai et al.
1 citations
NEJM Evidence
Pharmacological Effects and Toxicity Studies
41.22
article

Valproate Use by Fathers and Risk of Neurodevelopmental Disorders in Children

Hui-Min Chuang, Marleen M. H. J. van Gelder, Li Chen, HC Lai, Hedvig M E Nordeng, Lin-Chieh Meng, Fei-Yuan Hsiao
article en
1 citations

Abstract

Paternal use of valproate within the 90 days before conception was not associated with an increased risk of NDDs in offspring after adjustment for confounding in Norwegian and Taiwanese cohorts. (Funded by the Research Council of Norway and the National Science and Technology Council of Taiwan.).

NEJM EvidenceVol. 5(3)
Norwegian Institute of Public Health (NO), National Yang Ming Chiao Tung University (TW), National Taiwan University (TW), University of Oslo (NO), Taipei Veterans General Hospital (TW), Taipei Municipal YangMing Hospital (TW), National Taiwan University Hospital (TW), University of Pennsylvania (US)
Zero hunger
Openalex Percentile: Top 1%
Pharmacological Effects and Toxicity Studies
41.22
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