Fisetin-Mediated Topical Modulation of Senescent Cells in Skin Improves Wound Healing Dynamics in Diabetic Mice

Topical fisetin enhances diabetic wound healing by reducing fibrosis and promoting healthy dermal regeneration through senescence and inflammation modulation. [Figure: see text].

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Publication Details

Journal
Advances in Wound Care
Published
2026-02-23
DOI
https://doi.org/10.1177/21621918261426580
Primary Topic
Telomeres, Telomerase, and Senescence
Type
article
Field-Weighted Citation Impact
0.00
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article

Fisetin-Mediated Topical Modulation of Senescent Cells in Skin Improves Wound Healing Dynamics in Diabetic Mice

M. Mark Melin, K‐Raman Purushothaman, Barbara B. Hernandez-Rovira, Saranya P. Wyles et al.
Advances in Wound Care
Telomeres, Telomerase, and Senescence
article

Fisetin-Mediated Topical Modulation of Senescent Cells in Skin Improves Wound Healing Dynamics in Diabetic Mice

M. Mark Melin, K‐Raman Purushothaman, Barbara B. Hernandez-Rovira, Saranya P. Wyles, Margarita Carrasco-Jeldres, James L. Kirkland, Asfia Numani
article en

Abstract

Topical fisetin enhances diabetic wound healing by reducing fibrosis and promoting healthy dermal regeneration through senescence and inflammation modulation. [Figure: see text].

Advances in Wound Care
Cedars-Sinai Medical Center (US), Mayo Clinic (US), Mayo Clinic in Arizona (US)
Zero hunger
Openalex Percentile: Top 43%
Telomeres, Telomerase, and Senescence
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