One year of seizure freedom reduces premature death in people with epilepsy in rural China: A 10‐year cohort study

Mortality in this cohort remains more than twice that of the general population, with sudden death accounting for one third of cases. Achieving 1-year seizure freedom even once during follow-up substantially reduced mortality risk and altered cause-of-death distributions. This finding underscores seizure control as a practical and encouraging treatment goal in resource-limited settings.

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Publication Details

Journal
Epilepsia
Published
2026-02-24
DOI
https://doi.org/10.1002/epi.70173
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

One year of seizure freedom reduces premature death in people with epilepsy in rural China: A 10‐year cohort study

Guoxing Zhu, Ding Ding, Yan Ge, Bin Yang et al.
Epilepsia
Epilepsy research and treatment
article

One year of seizure freedom reduces premature death in people with epilepsy in rural China: A 10‐year cohort study

Guoxing Zhu, Ding Ding, Yan Ge, Bin Yang, Xiaowen Zhou, P. W. K. Kwan, Wenzhi Wang, Josemir W Sander
article en

Abstract

Mortality in this cohort remains more than twice that of the general population, with sudden death accounting for one third of cases. Achieving 1-year seizure freedom even once during follow-up substantially reduced mortality risk and altered cause-of-death distributions. This finding underscores seizure control as a practical and encouraging treatment goal in resource-limited settings.

Epilepsia
Chinese University of Hong Kong (HK), Sichuan University (CN), Fudan University (CN), West China Hospital of Sichuan University (CN), Jiaozuo University (CN), Beijing Institute of Neurosurgery (CN), National Hospital for Neurology and Neurosurgery (GB), Huashan Hospital (CN), University College London (GB), Epilepsy Society (GB), Monash University (AU)
Good health and well-being
Openalex Percentile: Top 50%
Epilepsy research and treatment
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