Unraveling CD4+ T cell heterogeneity and cell death-associated genes in high-grade serous ovarian cancer: a comprehensive analysis of single-cell RNA and spatial transcriptome sequencing
Our findings elucidate mechanisms of cell death-associated genes in CD4<sup>+</sup> T cell subgroups, with experimentally grounded biomarkers offering therapeutic options for HGSOC.
Authors
- Shaobo Wu
- Jiayi Yu (ORCID: https://orcid.org/0009-0000-4357-9073)
- Yaoyao Li
- Yurou Zhou
- Yanhong Lv
- Di Zhang
- Jun Tang
- Chunfeng Wu
- Lei Ding
Institutions
- Jinshan Hospital of Fudan University (CN)
- Anshan Hospital (CN)
Publication Details
- Journal
- Clinical & Translational Oncology
- Published
- 2026-02-24
- DOI
- https://doi.org/10.1007/s12094-026-04266-z
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 0.00